Thinning Hair
Thinning Hair

No one can stop hair loss completely. But you can have healthier, fuller and thicker hair while slowing down the rate of loss.


In androgenic hair loss, DHT causes susceptible hair follicles on the scalp to become smaller, turning the thicker, longer terminal hairs into thinner, shorter vellus hair. Reversing this process was once thought impossible—until minoxidil came along. 77 It has also been shown to be an effective treatment for alopecia areata, an inflammatory hair loss condition.

Terminal-type hair growth from vellus – size follicles was an unexpected side effect of minoxidil. It was originally primarily used as an orally-administered high blood pressure treatment drug designed to dilate vessels. 77 Determined to be safe and effective, minoxidil (in topical form) is one of two medications approved by the U.S. Food and Drug Administration to treat hair loss, with the brand name (Rogaine®) and generic products sold over-the-counter in many retail locations and through online retailers such as Amazon.com192

How Is Minoxidil Used?

Minoxidil is applied topically to the scalp to stimulate regrowth of hair, and comes in 2% and 5% concentrations. Original formulations of topical minoxidil combined it with propylene glycol, a common antimicrobial solution used with active pharmaceutical ingredients meant to be applied topically in preservative-free cream, liquid gel, lotion, and ointment forms. 216

While treatment must be continued to maintain results, some people report that this can be achieved with application once or twice weekly after using the product for 6-12 months. 20 Readily available forms of minoxidil are used in the following dosages, applied as directed to the scalp where there is thinning hair on top of the head: 13






5% foam ½ cap twice daily
Prescription only
5% topical solution 25 drops (1 mL) twice daily
Prescription only
2% topical solution 25 drops (1 mL) twice daily

Table 44: Minoxidil Dosages by Available Forms

It is often used in conjunction with hair transplant surgery to help maintain existing hair around the implants. Men who find the original topical solution form messy to apply may prefer the newer 5% foam formulation. Although it is only available in the higher concentration, minoxidil foam may actually have fewer side effects because it does not contain propylene glycol, an antibacterial ingredient used in the gel form. 192

Although it is not yet approved by the U.S. Food and Drug Administration, minoxidil administered via mesotherapy may be a safe and more effective way to regrow hair than topical minoxidil. In a 12 week clinical trial conducted by two universities in Egypt, 60 women with androgenetic (female pattern) hair loss were randomly assigned to two equal-sized treatment groups. One group was treated topical 2% minoxidil (2 mL/day), while the other group received 0.1 cc injections of 2% minoxidil (for every 2 cm of scalp area) once a week for a month and then once every other week for two months. Testing indicated that while both groups showed decreases in telogen hair percentage and increases in hair growth, the mesotherapy group outcomes were significantly better than the group using topical minoxidil. 217

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Over the counter meaning medicine you can buy at the store without a perscription.