Thinning Hair
Thinning Hair

No one can stop hair loss completely. But you can have healthier, fuller and thicker hair while slowing down the rate of loss.

How Does DHT Promote Hair Loss?

DHT binds to the androgen hormone receptors in the dermal papilla cells at the base of hair follicles.77 Its binding strength is five times that of testosterone and triggers certain genes that promote hair loss.(16) Studies indicate DHT is also three to seven times more potent than testosterone.84

One of the effects of DHT is miniaturization of hair follicles. Normal scalp hair follicles are the large terminal type, but in men and women with androgenetic hair loss scalp follicles shrink, the growth phase of the hair cycle is shortened, and the replacement hairs become fine and shorter.16

The increased transformation of testosterone to DHT by the enzyme 5α-reductase at the base of scalp follicles is variable. Some of the factors that influence DHT metabolism include the area of the scalp, gender, and age of onset:16

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